Ni-TED NUPharose Mag is a metal chelate affinity magnetic bead product primarily used for the rapid screening and purification of proteins with a histidine tag (His-tag). Its ligand is tris(carboxymethyl)ethylenediamine (TED) groups, the chelated metal ion is Ni2+, and the NUPharose Mag base matrix consists of agarose gel microspheres containing
paramagnetic material.

Compared to its corresponding column chromatography agarose resin (Ni-TED NUPharose FF), this product features the same ligand and maintains a good balance between affinity (capacity) and specificity (selectivity): while the binding capacity for His-tagged proteins exceeds 20 mg/mL, sample purity can reach over 90% after a single purification step, with Ni2+ content in the eluate comparable to environmental background levels, indicating extremely low metal ion leakage.